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| Impact
of Single-Voxel Spectroscopy (Probe SV) in routine
clinical practice |
| The Probe2000 Option offers
Single and Multiple Voxel Hydrogen Spectroscopy
with Automated Water Suppression and Gradient
Shimming. Spectroscopy results can be displayed
as Individual Voxel Spectra or as Color Metabolite
Maps. |
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| A
57 year old male presents with left hemisensory
deficit and increasing somnolence. MRI demonstrates
an enhancing right ganglionic mass (Figure A)
with central hyperintensity and surrounding edema
on the T2-weighted and FLAIR images (Figures B
& C). |
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| Differential diagnosis favored a tumor, however, an abscess
could not be excluded. Proton spectroscopy (PROBE-SV)
(Figure D) demonstrated a surprising lack of choline
(which would have indicated a tumor) with high
lipid and lactate indicating membrane breakdown,
necrosis, and anaerobic metabolism more suggestive
of an abscess. |
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As this
was early in our experience, the neurosurgeon
insisted on an MR-guided brain biopsy which
yielded toxoplasmosis (Figure E).
In AIDS
patients, proton spectroscopy can often make
the difference between biopsy and no biopsy
for necrotic lymphoma vs. toxoplasmosis. .
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"In addition to Probe SV,
GE's multi-voxel spectroscopy is easy-to-use and
technologist-friendly and provides higher resolution
spectra within 10 minutes"
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- William G. Bradley, M.D. |
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Required Equipment for Clinical Case
Magnet: 1.5T
Gradients: Base, HiSpeed or EchoSpeed
Computer: LX 8.3 software
Software: Probe2000 Upgrade
Software: Probe2000
(need to upgrade computer or gradients?
Click here to view the Upgrade Optimizer
- productivity gains)
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